Description
Title: Vascular tissues and tissue vascularization bioprinting scaffolds
Abstract: Tissue engineering has made significant strides in recent years toward the repair of damaged tissues. The development of extensive artificial tissue continues to be hampered by the vascularization of engineered tissues. Recent advances in biomaterials and three-dimensional (3D) printing allow for the manipulation of two or more biomaterials with complementary mechanical and/or biological properties to produce hybrid scaffolds that resemble natural tissues. Due to their tissue-like physical characteristics and capacity to incorporate living cells and/or biological molecules, hydrogels have emerged as crucial biomaterials. Additionally, dispensing-based bioprinting and other forms of 3D printing have advanced to the point where they can be used to create hybrid scaffolds with complex structures. The requirement for the necessary biomimetic nano-resolution combined with bioactive spatiotemporal signals continues to pose a challenge for current bioprinting techniques. The complexity of multi-material bioprinting and hydrogel synthesis also makes the creation of hybrid scaffolds difficult. This document displays An overview of the key characteristics of vascular systems, scaffold-based bioprinting techniques, and the materials and cell sources used will be given in order to create vascularized tissues. Additionally, we will discuss the technology’s current drawbacks and potential future directions while providing examples.
Keywords: tissue engineering; vascularization; scaffold; scaffold-free; hydrogels; biomaterials; 3D printing; bioprinting
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Bioengineering
Writer Experience: 20+ Years
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