Description
Title: Understanding Ascorbic Acid’s Therapeutic Potential in the Fight Against Cancer
Abstract: One of the leading causes of death worldwide is the fatal disease known as cancer. The side effects of anticancer medications continue to be a major concern despite various advancements in cancer prevention and treatment. Our bodies need ascorbic acid, an essential vitamin, for normal physiological function in addition to its antioxidant and anticancer properties. Ascorbic acid is abundant in foods and other natural sources and is also available as a nutritional food supplement, despite the fact that the body cannot produce it. Ascorbic acid has played a significant role in the development of anti-cancer drugs. role by preventing the metabolism of glucose, acting as an epigenetic regulator, scavenging reactive oxygen species (ROS), selectively producing ROS and encouraging their cytotoxicity against tumor cells, and controlling the expression of genes. HIF expression is seen in cancerous cells. To date, a number of ascorbic acid analogues have been created for their antioxidant and anticancer properties. The current review summarizes the biological mechanisms underlying ascorbic acid’s antitumor activity, lists its derivatives and their biological activity as anticancer agents, and discusses ascorbic acid’s anticancer patents as well as delivery methods like liposomes and nanoparticles.
Keywords: cancer; ascorbic acid; anticancer; antioxidant; pro-oxidant; epigenetic regulator; HIF
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Biomolecules
Writer Experience: 20+ Years
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