Description
Title: Tunable-sized silver nanoparticles that are antibacterial and antifungal that are embedded in different cellulose-based matrices
Abstract: In order to create silver nanoparticles (AgNPs) and assess their antimicrobial potential, this study used cellulose derivatives. Cellulose derivatives like hydroxypropyl cellulose (HPC), methylcellulose (MC), ethylcellulose (EC), and cellulose acetate (CA) were used as efficient reducing and stabilizing agents for AgNPs. Both the size of the resulting AgNPs and their capacity to reduce silver ions were compared. UV-Vis analysis was used to keep track of how the reduced AgNPs formed and held together in the solution. The AgNPs’ size, morphology, and charge were assessed. Using cellulosic derivatives, we discovered that AgNPs with sizes ranging from 17 to 89 nm and various stabilities could be produced. AgNPs’ stability is determined by factors like size and potential, with AgNPs-CA and AgNPs-HPC being deemed more stable than AgNPs-EC and AgNPs-MC because they exhibit higher potential values. The AgNPs also demonstrated antimicrobial activity against all clinical isolates and reference strains. Gram-positive and Gram-negative bacteria were both bactericidally affected by MIC concentrations between 0.0312 and 0.125 mM. At MIC 0.125 mM, the fungicidal effect was attained. These findings might offer logical justification for the design of medical gauze products, such as pads, rolls, and sponges.
Keywords: AgNPs; cellulose derivatives; antimicrobial activity; hydroxypropyl cellulose; methylcellulose; ethylcellulose; cellulose acetate
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Chemistry
Writer Experience: 20+ Years
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