Description
Title: Therapeutic Age-Reduction Techniques
Abstract: Progressive physiological changes occur as an organism ages. As a result of these modifications, normal biological processes are altered, including the capacity to handle metabolic stress, which ultimately results in cellular senescence. Genomic instability, telomere attrition, epigenetic changes, loss of proteostasis, nutrient sensing that is out of whack, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and altered intercellular communication are the nine hallmarks of the process itself. These characteristics are risk factors for pathologies like cancer, cardiovascular disease, and neurodegenerative illnesses. The examination of genetic pathways and biological processes in organisms that contain these nine hallmarks has been the main focus of recent evidence. From here, the therapeutic strategies can be discussed in an effort to slow down the aging process. In this review, information on the signs of aging and their relative contributions has been gathered, and in vitro and in vivo antiaging research experiments have been added. In order to promote healthy aging and extend human life expectancy with fewer side effects, this article will highlight the most significant antiaging strategies that researchers have suggested, including preventive measures, systemic therapeutic agents, and invasive procedures.
Keywords: aging; hallmarks; risk factors; therapeutic agent; antiaging strategies
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Biology
Writer Experience: 20+ Years
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