Description
Title: The WHO Manual for Human Semen Analysis, Sixth Edition: A Critical Review and SWOT Analysis
Abstract: The cornerstone of evaluating male fertility is semen analysis, with WHO guidelines serving as the global standard for procedure and reference values. Since the initial 1980 publication of the WHO manual, five additional editions have been made available over the past four decades. In July 2021, the 6th Edition appeared in print. We list the main updates to this edition’s sixth edition in this review. Additionally, we employ a SWOT (strengths, weaknesses, opportunities, and threats) analysis to assess the usefulness of this 6th Edition in clinical practice. The analysis of fundamental semen parameters has been strengthened in this new edition, which has taken into account previous editions’ shortcomings and gray areas. The procedures for measuring seminal oxidative stress and sperm DNA fragmentation are well-explained. The main innovation in this most recent edition is that it does away with the idea of reference thresholds and suggests “decision limits” in their place. This may sound appealing, but neither for basic semen parameters nor for extended or advanced parameters are any decision limits proposed. The changes and novelties in the WHO laboratory manual’s 6th Edition are summarized in this critical review along with a SWOT analysis, which offers a comprehensive analysis that might aid in its widespread use in the ensuing years.
Keywords: WHO laboratory manual 6th Edition; semen; sperm; sperm DNA fragmentation;oxidative stress; SWOT
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Biology
Writer Experience: 20+ Years
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