Description
Title: Study of Red Blood Cell Alloimmunization Frequency and Features in Thalassemic Patients: Multicenter Study from Palestine
Abstract: Earlier context. In Palestine, alassemia is a typical inherited hemolytic disorder. The main form of treatment is red blood cell (RBC) transfusion, but this can result in RBC alloimmunization. This study examined thalassemic patients in Palestine’s northern governorates to ascertain the prevalence and characteristics of RBC alloimmunization. Methods. In the thalassemia transfusion facilities in the northern Palestinian governorates, a prospective multicenter observational study was carried out. 215 thalassemia patients who frequently received blood transfusions were included in the study. Patients’ clinical and transfusion histories were reviewed. The microcolumn gel technique was used for antibody identification and screening. Results. In total, 218 patients were enrolled in the study. Males made up more than half (52.1%) of the patients. The average patient age was 18 years old (range: 12–24 years). A was the blood type that was most prevalent (40.5%). 12.6% of patients had alloantibodies found. The most frequently isolated antibodies were anti-D (33.3%), anti-K (25.9%), and anti-E (14.8%). Age, sex, the number of units transfused, the age at which the transfusion began, the history of splenectomy, and alloimmunization were not associated with one another. Conclusions. Anti-Rh and anti-K antibodies were prevalent in this patient group. Age, sex, the number of units transfused, the starting age of the transfusion, and previous splenectomy history could not predict the occurrence of alloimmunization.
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Medicine
Sub Category: Hematology
Writer Experience: 20+ Years
Plagiarism Report: Turnitin Plagiarism Report will be less than 10%
Restriction: Only one author may purchase a single paper. The paper will then indicate that it is out of stock.
What will I get after the purchase?
A turnitin plagiarism report of less than 10% in a pdf file and a full research paper in a word document.
In case you have any questions related to this research paper, please feel free to call/ WhatsApp on +919726999915
Reviews
There are no reviews yet.