Description
Title: Regulatory Roles of MicroRNAs in Cystic Diseases and Their Use as Potential Biomarkers: A Brief Review
Abstract: Nearly 60% of human genes are influenced by miRNAs, which are short endogenous conserved non-coding RNA molecules that regulate posttranscriptional gene expression through mRNA degradation or translational inhibition. While most cysts are benign, malignant cysts can develop inside benign cysts and are indicative of cystic diseases. Cystic diseases are characterized by the presence of abnormal fluid-filled sacs in the body. Recent research has shown that various cystic pathologies are influenced by the aberrant expression of several miRNAs found in extracellular fluids, such as plasma or serum, urine, saliva, follicular fluid, and semen. This review aims to describe the function of various miRNAs in three cystic diseases that are significant globally: pancreatic cyst tumors (PCTs), polycystic kidney disease (PKD), and polycystic ovarian syndrome (PCOS), as well as their potential application as novel biomarkers.
Keywords: microRNAs; cystic diseases; polycystic ovarian syndrome; polycystic kidney disease; pancreatic cyst tumors; biomarkers
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Biology
Writer Experience: 20+ Years
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