Description
Title: Regulatory Cell Death Responses in Viral Infections: A Review
Abstract: Abortive, productive, latent, and destructive infections are just a few of the different cellular responses that can result from a viral infection in the host. The three main categories of regulated cell death mechanisms—apoptosis, necroptosis, and pyroptosis—play crucial roles in the immune system’s response to viral infection. In necroptosis and pyroptosis, early membrane damage caused by an osmotic imbalance is manifested by cell shrinkage, nuclear condensation, bleb formation, and preserved membrane integrity. Many situations consider caspase-driven apoptotic cell death to be anti-inflammatory, and some pathogens use the cell death signaling pathways to launch a focused attack against the host. This review compiled the general principles and cellular signaling mechanisms of virus-host-specific molecule interactions and discussed in detail the selected mechanisms by which viruses interfere with cell death.
Keywords: cell death; death receptors; viral infection; signaling; regulated cell death
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Biology
Writer Experience: 20+ Years
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