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Research Paper on Oxidative Stress’ Effect on Stored Platelets

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Research Paper on Oxidative Stress’ Effect on Stored Platelets

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Title: Oxidative Stress’ Effect on Stored Platelets

Abstract: Five to six days are allotted for platelet storage and transfusion. One of the reasons why platelets are less effective and have a shorter shelf life is oxidative stress (OS). The studies on platelet storage have concentrated on enhancing the storage conditions by changing materials, temperature, and platelet storage solutions. However, it is still unclear how OS affects platelet survival while being stored. Consequently, this study was carried out to learn more about how platelets are affected by storage. At 22°C, platelets were kept for 12 days. A number of OS indicators were evaluated, including aggregation, superoxides, reactive oxygen species, glucose, pH, lipid peroxidation, protein oxidation, and antioxidant enzymes. As shown by increases in aggregation, superoxides, pH, conjugate dienes, and superoxide dismutase and decreases in glucose and catalase, OS increased during storage. Because of the antioxidant defense system, platelets could therefore withstand OS for up to 6 days while being stored. After day 8 of storage, there was a clear increase in OS, which can reduce the effectiveness of the platelets. The current study sheds light on the subtle changes taking place while platelets are being stored. This lays the groundwork for fresh opportunities to use different antioxidants as storage solution additives.

Paper Quality: SCOPUS / Web of Science Level Research Paper

Subject: Medicine

Sub Category: Hematology

Writer Experience: 20+ Years

Plagiarism Report: Turnitin Plagiarism Report will be less than 10%

Restriction: Only one author may purchase a single paper. The paper will then indicate that it is out of stock.

What will I get after the purchase?

A turnitin plagiarism report of less than 10% in a pdf file and a full research paper in a word document.

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