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Research Paper on NEXT-GENERATION SEQUENCED DATA HYBRID GENETIC DISEASE DIAGNOSTICS WITH SEMANTIC CAPABILITY

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Research Paper on NEXT-GENERATION SEQUENCED DATA HYBRID GENETIC DISEASE DIAGNOSTICS WITH SEMANTIC CAPABILITY

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Title: NEXT-GENERATION SEQUENCED DATA HYBRID GENETIC DISEASE DIAGNOSTICS WITH SEMANTIC CAPABILITY

Abstract: Genome sequencing technology called “next generation sequencing” is used in genetics to diagnose disease. Finding the one mutation in a genome that causes a disease is difficult even with the list of mutations that NGS provides. Numerous applications for variant prioritization have been created, but the information they offer is more like a suggestion than a diagnosis, and they also suffer from problems like misclassifying a nonpathogenic variant as a causal one or failing to pinpoint the causal gene. These problems prompted us to develop a variant prioritization strategy that makes use of the Exomiser and OMIM Explorer result sets that have been enhanced by semantic analysis of free-to-access abstracts and articles from the PubMed and PubMed Central databases. The Google Scholar repository will be used to search for scientific articles with a broader scope. We can present the most up-to-date and accurate knowledge about potential pathogenic variants thanks to the described methodology.

Keywords: gene prioritization, variant prioritization, semantical text analysis

Paper Quality: SCOPUS / Web of Science Level Research Paper

Paper type: Analysis Based Research Paper

Subject: Computer Science

Writer Experience: 20+ Years

Plagiarism Report: Turnitin Plagiarism Report will be less than 10%

Restriction: Only one author may purchase a single paper. The paper will then indicate that it is out of stock.

What will I get after the purchase?

A turnitin plagiarism report of less than 10% in a pdf file and a full research paper in a word document.

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