Description
Title: Modulators of Innate Immunity: Viral dUTPases
Abstract: The majority of free-living organisms have deoxyuridine triphosphate nucleotidohydrolase encoded for them (dUTPase; EC 3.6.1.23). In order to keep the pool ratio of dUTP to dTTP low, prevent dUTP from being incorporated into DNA by DNA polymerases, and provide a necessary precursor for dTTP biosynthesis, dUTPases represent a family of metalloenzymes. Thus, by stopping the uracilation of DNA, dUTPases contribute to the preservation of genomic integrity. Numerous mammalian DNA-containing viruses also have dUTPase encoding genes. This review will summarize studies showing that some dUTPases have novel functions that affect the host’s innate immune response in addition to their traditional enzymatic activity.
Keywords: deoxyuridine triphosphate nucleotidohydrolase; dUTPase; double-stranded DNA viruses
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Biomolecules
Writer Experience: 20+ Years
Plagiarism Report: Turnitin Plagiarism Report will be less than 10%
Restriction: Only one author may purchase a single paper. The paper will then indicate that it is out of stock.
What will I get after the purchase?
A turnitin plagiarism report of less than 10% in a pdf file and a full research paper in a word document.
In case you have any questions related to this research paper, please feel free to call/ WhatsApp on +919726999915
Reviews
There are no reviews yet.