Description
Title: Lung Organoids in Smoking Research: New Developments and Prospects
Abstract: It has been proven that tobacco use plays a role in the development of a number of respiratory illnesses, such as asthma, lung cancer, and chronic obstructive pulmonary disease (COPD). The lack of ex vivo experimental models and the murky results from animal models that can most accurately recapitulate the architecture and pathophysiology of the human lung, however, continue to be significant obstacles in mechanistic studies on the impact of smoking on human lungs. Organoids are proving to be a sophisticated ex vivo model that functionally and structurally mimics the human lungs better than other commonly used models, opening new research opportunities in the field of respiratory disease. This review will outline recent developments in lung organoid systems that may improve our understanding of the harmful and immunological effects of smoking on human lungs and make some recommendations for future research directions.
Keywords: lung organoids; lung progenitors; stem cells; tobacco smoking; COPD
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Biomolecules
Writer Experience: 20+ Years
Plagiarism Report: Turnitin Plagiarism Report will be less than 10%
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