Description
Title: Improved Cancer Theranostics with Hydroxyapatite Nanoparticles
Abstract: Hydroxyapatite nanoparticles (HAp NPs), in addition to their well-known uses in bone tissue engineering, have shown great promise for enhanced cancer therapy. In comparison to traditional chemotherapeutic methods, HAp NPs’ chemical structure provides excellent opportunities for loading and delivering a wide variety of anticancer drugs in a sustained, prolonged, and targeted manner. Another strategy for delivering advanced anticancer effects, such as the capacity to inhibit the growth and metastasis of cancer cells by activating particular cell signaling pathways, is the incorporation of specific therapeutic elements into the basic composition of HAp NPs. This strategy can be used alone or in combination with drug release. By using various surface modification techniques, it is simple to transform HAp NPs into smart anticancer agents that make it easier to target and kill cancer cells while having little to no negative effects on healthy, normal cells. Magnetic and nuclear in vivo imaging applications in cancer diagnosis are also promising because superparamagnetic HAp NPs now make it possible to detect solid tumor cells. The focus of ongoing research is on using HAp NPs to create three-dimensional scaffolds for the treatment of cancerous tissues or organs while promoting the regeneration of healthy tissue following the detection and removal of cancer. A summary of HAp NP applications in cancer theranostics is given in this review, along with a discussion of the field’s current constraints and future obstacles to the opening of new research directions.
Keywords: bioceramics; hydroxyapatite; nanomaterials; cancer treatment
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Biology
Writer Experience: 20+ Years
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