Description
Title: Developing Anti-Biofilm Dental Polymeric Restorative Materials: Emerging Contact-Killing Antibacterial Strategies
Abstract: For repairing tooth cavities, bonding tooth-colored fillings, sealing root canal systems, and many other dental restorative applications, polymeric materials are the first choice. However, bacterial colonization and attachment to polymeric materials are very likely to result in dental disease. diseases. The formation of biofilms over polymeric restorative materials and at the tooth/material interfaces has been investigated using a variety of strategies. One of them, contact-killing substances, has demonstrated promising results in thwarting dental biofilms. In contrast to materials that rely on release, contact-killing substances can be immobilized within the polymer structure to produce a long-lasting effect with no leaching or release. This review talks about contemporary investigation into the creation of contact-killing substances in dental restorative materials to combat oral pathogens Contact-killing substances have shown promise as antibacterial agents in resin composite restorations, dental adhesives, root canal sealants, denture-based materials, and crown cements. Several oral pathogens linked to dental caries, periodontal diseases, endodontic, and other conditions have been found to be effectively inhibited by contact-killing restorative materials. fungus infections, etc. The clinical applicability of this new generation of contact-killing dental restorative materials needs to be confirmed through additional laboratory optimization and clinical trials using translational models.
Keywords: antibacterial agents; polymers; dental caries; biofilms; composite resins
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Bioengineering
Writer Experience: 20+ Years
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