Description
Title: Current Situation and Future Challenges in Integrin-Mediated Delivery of Drugs and Nucleic Acids for Anti-Angiogenic Cancer Therapy
Abstract: Angiogenesis, the growth of new blood vessels from pre-existing vasculatures, is essential in controlling the development of tumors. The angiogenic potential of tumor endothelial cells is controlled by binding interactions between integrin, a heterodimeric transmembrane glycoprotein receptor, and its extracellular matrix (ECM) protein ligands. Integrin receptors are desirable targets in the treatment of cancer because they are overexpressed on tumor endothelial cells but not on blood vessels that are at rest. The use of these receptors in anti-angiogenic therapy is growing due to the targeted delivery of chemotherapeutic agents and nucleic acids to tumor vasculatures. The current article makes an effort to give a retrospective account of previous developments, highlight significant recent contributions, and point out any unresolved problems in this developing field.
Keywords: Integrin; drug delivery; angiogenesis; anti-angiogenic therapy; siRNA; tumor-homing peptides; combination delivery of drug and nucleic acids
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Bioengineering
Writer Experience: 20+ Years
Plagiarism Report: Turnitin Plagiarism Report will be less than 10%
Restriction: Only one author may purchase a single paper. The paper will then indicate that it is out of stock.
What will I get after the purchase?
A turnitin plagiarism report of less than 10% in a pdf file and a full research paper in a word document.
In case you have any questions related to this research paper, please feel free to call/ WhatsApp on +919726999915
Reviews
There are no reviews yet.