Description
Title: Curcumin’s Biomedical Uses and Bioavailability: An Updated Overview
Abstract: The bioactive compound responsible for many of turmeric’s pharmacological effects, including its anticancer, antimicrobial, anti-inflammatory, antioxidant, and antidiabetic properties has been identified as curcumin, a yellow-colored molecule derived from the rhizome of Curcuma longa. Despite this, curcumin’s clinical use is insufficient due to its poor absorption, quick metabolism, and low solubility. Recent developments in research have identified a number of elements and methods to boost curcumin’s bioavailability. Synthetic derivatives and structural analogs of curcumin have demonstrated increased efficiency and bioavailability, thereby expanding the range of applications of curcumin. These methods include combining with adjuvants, encapsulating in carriers, and formulating in nanoforms in combination with other bioactive agents. Expanding the biomedical applications and clinical efficacy of curcumin would be made possible by the potential incorporation of biotechnology and nanotechnology in addressing the current drawbacks. As a result, we give a thorough overview of the numerous therapeutic potentials of curcumin in this review, as well as its limitations in effective clinical applications and recent developments that have increased its bioavailability for use in a variety of biomedical applications.
Keywords: curcumin; bioavailability; antibiotics; anticancer agents; nanomedicine; pharmaceutical formulations
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Biology
Writer Experience: 20+ Years
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