Description
Title: Cancer Labeling, Resection, and Treatment Using Fluorescent Anti-CEA Antibodies: A Review
Abstract: The difficulty in detecting and visualizing tumor margins in primary and metastatic disease is a significant impediment to the diagnosis and effective treatment of solid-tumor cancers. Fluorescence can improve the surgeon’s capacity for cancer detection and support cancer resection. Carcinoembryonic antigen (CEA) is expressed by a number of cancer types, including gastric, pancreatic, and colorectal cancer. Near-infrared fluorescent dyes have been used to label CEA antibodies that have been developed. The use of CEA antibodies coupled to fluorescent probes for in vivo studies since 1990 was reviewed in this review article. 900 titles and abstracts were screened after searches were made in the PubMed and Google Scholar databases. Ninety-nine entries were fully reviewed after being flagged as possibly meeting inclusion or exclusion criteria. The review included forty articles, and it looked through the citations of those articles to find more entries. The final review included a total of 44 articles. In murine models as well as in humans, it has been demonstrated that fluorescent anti-CEA antibodies improve tumor detection and resection. The combined findings show that fluorescent-conjugated anti-CEA antibodies have significant potential to enhance cancer surgery and diagnosis. Anti-CEA fluorescent antibodies have also been used successfully for photoimmunotherapy treatment of cancer in a new technology.
Keywords: carcinoembryonic antigen; CEA; fluorescence-guided surgery; FGS; infrared dyes; fluo-rescence; fluorescence labeling
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Biomolecules
Writer Experience: 20+ Years
Plagiarism Report: Turnitin Plagiarism Report will be less than 10%
Restriction: Only one author may purchase a single paper. The paper will then indicate that it is out of stock.
What will I get after the purchase?
A turnitin plagiarism report of less than 10% in a pdf file and a full research paper in a word document.
In case you have any questions related to this research paper, please feel free to call/ WhatsApp on +919726999915
Reviews
There are no reviews yet.