Description
Title: Blood Profile Changes in Sickle Cell Anemia Patients Admitted for Vaso-occlusive Crisis and Acute Chest Syndrome from a Steady State
Abstract: Acute chest syndrome (ACS) will occur at least once in the lifetime of nearly half of all sickle cell disease (SCD) patients. The development of ACS involves numerous inflammatory cascade-related cells and molecules. When compared to a separate admission for a vaso-occlusive crisis (VOC) without ACS development, we discovered that patients with SCD who experienced ACS as a side effect of a VOC had a significant rise in leukocytes and fall in platelets from their steady state. Between the two admissions, there was no discernible difference in hemoglobin or reticulocyte count from steady state. These findings suggest that trending laboratory markers may be helpful in identifying patients who are at risk for developing ACS.
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Medicine
Sub Category: Hematology
Writer Experience: 20+ Years
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