Description
Title: A current review of pharmacological treatment for pulmonary arterial hypertension
Abstract: A rare and fatal condition known as pulmonary hypertension (PHTN) causes pulmonary arterial pressure and pulmonary vascular resistance to gradually rise, which ultimately results in right ventricular failure and death. Pulmonary arterial hypertension (PAH) does not currently have a known cure, but over the past ten years, targeted pharmaceutical options have become available. A thorough physical examination and conclusive diagnostic testing are required to make a definitive diagnosis of pulmonary arterial hypertension prior to consideration of therapeutic options. The preferred screening method is still echocardiography, and right heart catheterization is the gold standard for a conclusive diagnosis. Based on a diagnostic algorithm and the patient’s disease severity, therapeutic options may be available once PAH has been diagnosed. Different drug classes with various modes of action are available that have a vasodilatory effect and enhance exercise tolerance, quality of life, and survival.
Keywords: pulmonary arterial hypertension, phosphodiesterase type 5 inhibitors, endothelin receptor antagonist, prostacyclin analogues, right heart catheterization
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Advances in Respiratory Medicine
Writer Experience: 20+ Years
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