Description
Title: A Cross-Sectional Study of Heritable Thrombophilia in Venous Thromboembolism in Northern Pakistan
Abstract: Background. Venous thromboembolism (VTE), which can be fatal but is preventable, is defined as the development of clots in a deep vein or the lodging of thrombus towards the lungs. e risk of developing VTE can go up for a number of reasons. Where there are countless acquired causes, inherited thrombophilia cannot be discounted as a possibility. In light of this, we have tested for inherited thrombophilia in all patients with venous thromboembolism. Objective. to assess the prevalences of prothrombin gene mutations, Factor V Leiden, protein C and S deficiencies, and antithrombin (AT) deficiency in patients with venous thromboembolism. Materials and procedures From July 2016 to June 2017, a study involving 880 patients who had venous thromboembolism symptoms was carried out. The thrombophilia defects AT, protein C and S deficiencies, Factor V Leiden, and prothrombin gene mutations were examined in a blood sample taken from patients. All acquired thrombosis-causing factors were disregarded. Results. 182 of the 880 patients who underwent thrombophilia screening showed a history of VTE. They ranged in age from 1 to 58. Males made up the majority of the group. There was evidence of heritable thrombophilia in 45 patients (24.7%). Twenty of them (10.9%) had ATdeficiency, nine (4.9%) had Factor V Leiden mutation, six (3.2%) had protein C deficiency, and five (2.7%) had both protein S deficiency and prothrombin gene mutation. Conclusion. In comparison to other thrombophilia defects that were looked into, our study showed the highest frequency of antithrombin deficiency.
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Medicine
Sub Category: Hematology
Writer Experience: 20+ Years
Plagiarism Report: Turnitin Plagiarism Report will be less than 10%
Restriction: Only one author may purchase a single paper. The paper will then indicate that it is out of stock.
What will I get after the purchase?
A turnitin plagiarism report of less than 10% in a pdf file and a full research paper in a word document.
In case you have any questions related to this research paper, please feel free to call/ WhatsApp on +919726999915
Reviews
There are no reviews yet.