Description
Title: Metabolic Engineering Methods for Microbes’ Co-Utilization of Carbon Sources
Abstract: An important area of study in metabolic engineering is the co-utilization of carbon sources in microbes. It is not only an effort to lower the price of microbial production but also increasing target product yields or reducing the production of byproducts However, there are obstacles to the co-utilization of carbon sources in microbes, like the suppression of carbon catabolite. Different metabolic engineering techniques, such as deactivating the phosphotransferase system and rewiring carbon assimilation pathways, have been developed to get around the obstacles. The most recent advancements in various strategies that help microbes use two or more carbon sources simultaneously are summarized in this review. The co-utilization of glucose and pentoses, two of the main sugars in lignocellulose, is the main topic of discussion.
Keywords: metabolic engineering strategies; co-utilization; lignocellulosic biomass
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Bioengineering
Writer Experience: 20+ Years
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