Description
Title: DNA Adductomics: A Revolutionary Tool in Biomedical Research, with Applications in Chemically Induced Adverse Outcomes
Abstract: Adductomics is a new and developing field in toxicological research that focuses on the adducts created when biological molecules in living organisms react with reactive chemical agents. The use of adductomics in interdisciplinary sciences was facilitated by advancements in analytical techniques. This review aims to bring in a fresh perspective by offering in-depth analyses of various adductomics applications in addressing some of society’s most pressing problems. Focusesing on a variety of adductomics applications, such as predicting the risk of chronic diseases brought on by reactive agents and predicting carcinogenesis brought on by tobacco use; determining the toxicity of chemical agents and enhancing genotoxicity studies; developing customized medications and precision cancer chemotherapy; assessing the quality or extent of pollution in the environment using biological systems; and developing diagnostic tools and methods It is difficult to characterize adducts that are present in very low concentrations, and the lack of a dedicated database to identify adducts is further complicating the issue of adduct diagnosis. In order to accurately assess adducts, it is also possible to improve sample preparation techniques, data processing software, and algorithms.
Keywords: adductomics; DNA adduct; protein adduct; cancer detection tool
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Biology
Writer Experience: 20+ Years
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