Description
Title: Malaria vaccines against Plasmodium falciparum and adjuvants for vaccines
Abstract: A global health issue, malaria is a parasite-vector-borne disease caused by Plasmodium spp. Plasmodium falciparum has been found to be the most lethal of the Plasmodium spp. species that cause malaria in humans. The illness can cause anything from a slight fever and shivering to hemolytic anemia and neurological problems. Malaria is a persistent issue due to the emergence of drug resistance and the lack of reliable vaccines. Although there has been progress in our understanding of the parasite’s host response, many aspects of the parasite’s biology in its mammalian host remain unknown. In this setting, there is a pressing need for the creation of efficient therapeutic and preventive measures, such as brand-new medications and innovative vaccines with adjuvants that induce protective immunity. In the current article, various vaccine candidates are discussed along with an overview of the current understanding of anti-malarial immunity against P. falciparum. The mechanism of action of vaccine adjuvants that are clinically used has received particular attention.
Keywords: anti-malarial drugs; malaria vaccine; Plasmodium falciparum; vaccine adjuvants
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Biology
Writer Experience: 20+ Years
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