Description
Title: A Tale of Viral Exploitations and Host Reactions: Dengue Virus Infection
Abstract: The Dengue virus is the cause of the arboviral disease dengue, which is spread by mosquitoes. With no effective vaccines, it is one of the major public health issues in tropical and subtropical areas. Around 400 million people worldwide contract the dengue virus each year, and patients with severe dengue have a 20% mortality rate. The Dengue virus is an enveloped, single-stranded, positive-sense RNA-containing virus that is a member of the Flaviviridae family. Studies on this virus’s infection cycle have uncovered potential host targets that are crucial to the virus’s replication cycle. In this review article, we’ll talk about the various stages of the Dengue virus infection cycle inside mammalian host cells, how the virus takes advantage of host proteins during infection, and how the host fights back by inducing various antiviral responses.
Keywords: Dengue virus; viral pathogenesis; Dengue genome; viral replication; inflammation; host immune response; cytokine storm; Antibody Dependent Enhancement (ADE); apoptosis; autophagy
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Biology
Writer Experience: 20+ Years
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