Description
Title: Possibilities of Vitamin C as an Additive in Blood Plasma Stored
Abstract: It is imperative to enhance blood storage and extend the shelf life of blood. Oxidative stress (OS) in blood and its impact on plasma with storage have only been the subject of a very small number of studies. This study aims to I explain the ongoing oxidant levels and antioxidant status changes in plasma during storage and (ii) assess the role of vitamin C (VC) as an additive during blood storage. Male Wistar rats’ blood was drawn and kept at 4°C for 25 days. The experimental group received blood samples, while the control group did not. Every five days, plasma was isolated and the products of protein oxidation, lipid peroxidation, and OS were examined. In all groups with storage, catalase activity rose. Although lipid peroxidation was maintained in VC (30) and VC (40), it decreased in VC (10). (60). Carbonyls were maintained toward the end of storage, despite variations in all groups. The amount of advanced oxidation protein products (AOPP) increased in VC (30) and remained constant in VC (10) and VC (30). (60). All groups maintained sulfhydryls. It now allows for further research on vitamin C in combination with other antioxidants, in storage solutions, since vitamin C was unable to sufficiently reduce OS.
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Medicine
Sub Category: Hematology
Writer Experience: 20+ Years
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