Description
Title: A Systematic Review of the Effectiveness of Different Chemotherapeutic Agents for Decontaminating Infected Dental Implant Surface
Abstract: Evaluation of the best chemotherapeutic drug for decontaminating infected dental implants is the objective. Materials and techniques Using the PRISMA guidelines, a comprehensive electronic literature search was conducted between January 2010 and December 2021 in MEDLINE (PubMed) and Google Scholar. Five studies about the chemical cleaning of dental implants were looked at in total. The PICOS framework served as the basis for the search strategy. The study included randomized controlled trials (RCTs) and cohort studies assessing the efficiency of various chemotherapeutic agents for the decontamination of dental implants. After comparing the chemotherapeutic agents used in the qualifying studies, the outcome variable examined was the most efficient chemotherapeutic agent(s) for dental implant surface decontamination. As a result, 1380 articles were eliminated from the basic database of 1564 records because they were redundant, irrelevant, or both. Moreover, 134 articles were purposefully left out of 184 studies. Thirteen studies were shortlisted after more filtration. Utilizing the risk of bias assessment tool, two researchers (SSA and SA) evaluated the caliber of the studies that were chosen. Five articles were finally included in the current systematic review after eight studies were excluded. Conclusion: There is insufficient information available to draw a firm conclusion about the effectiveness of chemotherapeutic agents in cleaning contaminated titanium surfaces. The most widely used chemotherapy drugs, however, are sodium hypochlorite (1%), citric acid (40%) and chlorhexidine (CHX) (0.2%, 0.12%). Of these, citric acid demonstrated the greatest potential for removing biofilm from the contaminated implant surface. Sodium hypochlorite (0.1%), citric acid (40%) and CHX (0.2%) can all be suggested as therapeutic agents along with their curbs.
Keywords: decontamination; peri-implantitis; peri-implantitis treatment; dental implant; biofilm removal; implant surface; chemotherapeutic agents; chemical decontamination
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Antibiotics
Writer Experience: 20+ Years
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