Description
Title: Orthopedic Surgical Site Infections in a Teaching Hospital in Madhya Pradesh, India: Antibiotic Use, Incidence, and Risk Factors
Abstract: The overall surgical site infection (SSI) events worldwide are influenced by orthopedic surgeries. SSI rates in India range widely (1.6-38%), but there is no widespread system for monitoring them. The purpose of this study is to determine the prevalence of SSIs, risk factors, patterns of antibiotic prescription, and susceptibility among orthopedic patients who have undergone surgery in an Indian teaching hospital. 1205 patients’ data were gathered between 2013 and 2016. The European Centre for Disease Prevention and Control’s recommendations were used to identify SSIs. The classification system of the American Society for Anesthesiologists was used to forecast the operative risk of patients. Backward stepwise logistic regressions with one and more variables were run. Over the course of three years, 7.6% of patients experienced SSIs. Staphylococcus aureus (7%), the most prevalent SSIs-causing microorganism, had strains that were 100% resistant to penicillin, 80% resistant to erythromycin, 80% resistant to cotrimoxazole, 60% resistant to amikacin, and 60% resistant to cefoxitin. The most common antibiotic prescribed (36%) was amikacin. Significant risk factors included male sex (OR 2.64; 95% CI 1.32-5.30), prior hospitalization (OR 2.15; 95% CI 1.25-3.69), prescription of antibiotics while hospitalized before perioperative antibiotic prophylaxis (OR 4.19; 95% CI 2.51-7.00), and postoperative length of stay > 15 days (OR 3.30; 95% CI 1.83-5.95). Additionally, although it has not yet been confirmed in the literature, preoperative showering significantly increased the risk of SSI (OR 4.73; 95%CI 2.72-8.22).
Keywords: surgical site infections; SSI; incidence; risk factors; orthopedic; antibiotic susceptibilitypatterns; private ; teaching; tertiary care hospital; India
Paper Quality: SCOPUS / Web of Science Level Research Paper
Subject: Antibiotics
Writer Experience: 20+ Years
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