Research Paper on Sickle cell disease’s pulmonary complications: a narrative clinical review

Description

Title: Sickle cell disease’s pulmonary complications: a narrative clinical review

Abstract: Vaso-occlusive episodes affecting various organs are linked to sickle cell disease (SCD). In this patient population, pulmonary involvement is a major cause of morbidity and mortality. We searched the PubMed database for articles that discussed pulmonary diseases and SCD. A new radiodensity on a chest radiograph with a disease-consistent history is referred to as an acute chest syndrome. Blood transfusions, pain medication, and broad-spectrum antibiotics are all used in treatment. Functional asplenia brought on by microvasculature infarcts raises the possibility of contracting an encapsulated organism infection. The mortality rate from pulmonary infections has been significantly reduced by widespread vaccination programs and antibiotic prophylaxis. Patients with SCD should receive the same care for venous thromboembolism as healthy people. Patients with SCD who have pulmonary hypertension also have a higher mortality rate. The treatment options recommended by the American Thoracic Society depend on the underlying cause and are either aimed at treating SCD directly, using vasodilator drugs if the patient belongs to group 1, or using long-term anticoagulation if the patient belongs to group 4. (in terms of etiology). Compared to controls, patients with SCD are more likely to experience asthma symptoms. Patients who experience recurrent vaso-occlusive events or unexplained nocturnal and daytime hypoxemia should be evaluated for sleep disorders of breathing. Finally, it is still unknown how useful pulmonary function tests are.

Keywords: sickle cell disease, acute chest syndrome, pneumonia, venous thromboembolic disease, pulmonary hypertension

Paper Quality: SCOPUS / Web of Science Level Research Paper

Subject: Advances in Respiratory Medicine

Writer Experience: 20+ Years

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